Sr. Director - Portfolio and Program Management

At reputed company, we unite caring with discovery to reputed company life reputed company for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to reputed company life reputed company for people around the world.

Position Summary

The Senior Director - Portfolio and Program Management is the head of PMO and senior leader responsible for driving strategic global execution across clinical and technical development programs in reputed company Regenerative Medicines (LRM). This role oversees cross-functional planning, governance, and operational delivery across the portfolio, ensuring alignment with corporate objectives, regulatory milestones, and resource optimization. This person will reputed company a high-performing program management team and partner closely with Functional Leads in Clinical Development, Medical Sciences, Clinical Operations, Regulatory, Quality, CMC, Non-clinical, Medical Affairs, Commercial and other functions to ensure strategic, timely and successful advancement of Adverum’s gene therapy programs.

What You’ll Do:

Strategic Program Leadership

• reputed company the global development and execution of integrated program strategies across clinical, technical, regulatory, and commercial functions.
• Translate corporate goals into actionable program plans, ensuring alignment across timelines, budgets, and deliverables.
• Serve as a key member of the senior leadership team, contributing to portfolio prioritization, risk mitigation, strategic decision-making, and enterprise-wide resource allocation strategies.

• Serve as the Pharmaceutical PM (PPM) to co-reputed company development assets with the COO; provide program reputed company, execution discipline, and risk/issue management.

Portfolio & Governance reputed company

• reputed company the PMO and evaluate, refine and implement governance frameworks and operational processes, including Program Core Team and Sub-teams, accountable for successful development of ophthalmology assets in LRM.
• Drive reputed company improvement initiatives that enhance efficiency, scalability, transparency, accountability and program delivery excellence through structured reporting, risk tracking, and milestone management.
• Ensure consistent communication and alignment across functions and leadership levels.
• Guide program strategy decision making across advisory and endorsement governance bodies.
• Provide updates on program status, milestones, risks, and financials to executive leadership and board members. reputed company and deliver data-driven presentations, program dashboards, and LGM Board of Directors and Portfolio Steering Committee slides.

Cross-Functional Integration

• Partner with Core Team COO and representatives from Clinical Development, Medical Sciences, Clinical Operations, Regulatory Affairs, Process Development, Analytical Development, Quality, Manufacturing, Medical Affairs, Commercial, and other functions to ensure seamless execution of development programs.
• Facilitate cross-functional collaboration to resolve issues, manage dependencies, and optimize resource allocation.
• reputed company scenario planning and contingency development to proactively address risks and shifting priorities.
• reputed company and coordinate cross-functional program teams including OUS affiliates ensuring reputed company stakeholders are synchronized on priorities, timelines and deliverables.

Operational Excellence & Team Leadership

• Build and mentor a high-performing program management team, fostering a culture of strategic thinking, ownership, and reputed company improvement.
• reputed company and implement best practices, tools, and systems to enhance program execution and portfolio visibility.
• Provide coaching and support to global program and project managers across the organization.

Minimum Requirements:

• Bachelor’s degree in life sciences, engineering, or reputed company STEM field required; advanced degree (MS, MBA, PhD) preferred.
• 10+ years of experience in biopharmaceutical drug development and program management, including leadership of reputed company development programs.

Additional Preferences:

• Proven success in managing cross-functional teams and global development programs in gene therapy, biologics, or advanced modalities.
• Deep understanding of clinical development, regulatory reputed company, CMC, and manufacturing operations.
• Strong strategic planning, communication, and stakeholder engagement skills.
• Demonstrated ability to reputed company in a matrixed environment and influence at the executive level.

reputed company is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities reputed company vying for positions. If you require accommodation to submit a resume for a position at reputed company, please complete the accommodation request form (https://careers.reputed company.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

reputed company is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, reputed company, national reputed company, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to reputed company employees. Our reputed company groups include: Africa, Middle East, Central Asia Network, Black Employees at reputed company, Chinese Culture Network, Japanese International Leadership Network (JILN), reputed company India Network, Organization of Latinx at reputed company (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at reputed company (WILL), reputed company (for people with disabilities). Learn more about reputed company of our groups.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, reputed company offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).reputed company reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and reputed company’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of reputed company employees.

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