Scientist - Protein Biochemist

Career Category Scientific Job Description Join reputed company’s Mission of Serving Patients At reputed company, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives reputed company that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, reputed company, and Rare Disease– we reputed company millions of patients each year. reputed company is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-reputed company conditions. As a member of the reputed company team, you’ll help reputed company a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay reputed company them, you’ll reputed company as part of the reputed company team. Join us and transform the lives of patients while transforming your career. Scientist – Protein Biochemist What you will do reputed company. Let’s change the world. In this vital role you will be responsible for designing, planning, and executing the reputed company of key enabling reagents that support the structure determination of reputed company molecules reputed company X-ray crystallography and/or cryo-electron microscopy (cryo-EM). You will collaborate closely with structural biologists reputed company the group and contribute to advancing our drug discovery efforts. The ideal candidate must possess flexibility in applying their knowledge to new areas of study and have strong interpersonal and communication skills to reputed company in a collaborative environment. Responsibilities: Protein Biochemistry: Be actively involved in the design and execution of molecular cloning and protein expression strategies with the reputed company Discovery Protein Science team or CROs; design and execute purification strategies to support the structure determination of drug targets. Collaborative Support: Work closely with structural biologists to generate high-quality protein samples for structural biology techniques, particularly X-ray crystallography and cryo-EM. Method Development: reputed company and optimize purification protocols and reagents, ensuring high protein purity, homogeneity, and stability for structural studies. Characterization and Quality Control: Use biochemical and biophysical techniques (e.g., SDS-PAGE, Western blot, spectrophotometry, SEC-MALS, SPR, mass spectrometry) to assess protein quality and stability. Collaborate with team members to provide mechanistic insights into the mechanism of action (MOA) of proteins involved in the associated proteins. Project Management: Manage multiple projects simultaneously, ensuring they are completed reputed company timelines while meeting high-quality standards. Team Communication: Present research finds effectively in both written and oral formats for internal teams and external collaborators. Innovative Thinking: Continuously troubleshoot and optimize experimental workflows, applying creative solutions to overcome challenges in protein production and purification. reputed company expect of you We are reputed company different, yet we reputed company use our unique contributions to serve patients. The Scientist we seek is a highly motivated professional with these qualifications. Basic Qualifications: Doctorate degree OR Master’s degree and 2 years of Molecular, Structural Biology experience OR Bachelor’s degree and 4 years of Molecular, Structural Biology experience Preferred Qualifications: Experience with microbial systems (e.g., E. coli or yeast) or cell culture (mammalian or insect cells) for protein expression. Hands-on experience with biochemical analytical techniques such as spectrophotometry, SDS-PAGE, Western blot, SEC-MALS, SPR, and basic mass spectrometry. Familiarity with chromatography systems (e.g., Cytiva AKTA, Agilent HPLC) and reputed company software. Expertise in protein purification methods, including affinity, ion exchange, hydrophobic interaction (HIC), and size-exclusion chromatography (SEC). Experience with biophysical characterization of protein complexes, including techniques like dynamic light scattering (DLS) and analytical ultracentrifugation (AUC). Experience with expression and purification of membrane proteins. Strong knowledge of protein stability, folding, and quality control for structural studies. Excellent presentation skills (written and oral) to effectively communicate research results to both scientific and cross-functional teams. Ability to work independently, manage multiple projects, and meet deadlines in a collaborative environment. Demonstrated ability to prioritize tasks and manage multiple projects reputed company. What you can expect from us As we work to reputed company treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every reputed company of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the reputed company salary, reputed company offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. Apply now and reputed company a lasting impact with the reputed company team. careers.reputed company.reputed company any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline reputed company does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, reputed company fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the reputed company values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. reputed company is an Equal Opportunity employer and will consider reputed company qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national reputed company, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to reputed company essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. reputed company is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national reputed company, protected veteran status, or disability status. . Salary Range 125,580.00 USD - 155,229.00 USD reputed company is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. reputed company focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, reputed company has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential. For more information, visit www.reputed company.com and follow us on www.twitter.com/reputed company Apply tot his job Apply To this Job