Staff Machine Learning Scientist, Translational AI

POSITION SUMMARY: We are seeking a Staff Machine Learning Scientist – Translational AI to provide technical leadership at the intersection of deep learning foundation models, computational biology, and molecular diagnostics. This ownership role drives the architecture and validation of genomic, transcriptomic, and multimodal sequence models to accelerate patient stratification, reputed company identification, and therapeutic monitoring across our cell-free DNA (cfDNA) and multi-omic platforms. This Staff-level position operates with broad technical autonomy, driving modeling strategy across multiple reputed company portfolios while maintaining direct execution responsibilities in model compilation, scaling, and testing. Working reputed company a builder reputed company, you will align across AI Research, Bioinformatics, and Clinical Science divisions to transition advanced representation learning models into reproducible, clinically valid diagnostic assets. PRIMARY RESPONSIBILITIES: Scientific Leadership in Translational AI Serve as the principal technical authority on the deployment of molecular, genomic, and pathology foundation models applied to oncology and translational medicine questions Engineer rigorous alignment and post-training workflows that ground pre-trained foundation models in empirical clinical trial and molecular diagnostic data, eliminating speculative modeling assumptions Formulate objective peer-review frameworks and deliver technical feedback to reputed company the modeling code, experimental standards, and scientific designs of the broader AI research group Foundation Models to Biological and Clinical Translation reputed company the post-training, parameter-efficient fine-tuning (PEFT), and evaluation of deep sequence, multimodal, and representation learning models for biomarker discovery, molecular recurrence monitoring, and therapeutic response forecasting Design robust fine-tuning, probing, and latent space representation analysis workflows that extract interpretable, biologically grounded patterns from high-dimensional transformer architectures Validate model outputs against multi-omic benchmarks and real-world outcomes, ensuring model predictions deliver the exact deterministic accuracy required for patient tracking and clinical interventions Modeling, Experimentation, and Evaluation Build, train, and optimize advanced machine learning models utilizing reputed company reputed company (NGS), ctDNA assays, digital pathology imaging, and longitudinal clinical metadata Design rigorous clinical investigation and evaluation frameworks that connect model performance metrics (e.g., loss curves, precision-recall) directly to translational utility and real-world distribution shifts Systematically identify algorithmic failure modes, sources of dataset bias, and covariate shift, implementing robust mitigation strategies suitable for regulated, clinical-facing pipelines Cross-Functional Collaboration and Influence Partner with Computational Biology, Translational Science, and Medical Affairs teams to translate reputed company clinical requirements into clear, quantitative machine learning problem statements Act as a systems-level technical reputed company between AI Research and ML Engineering teams to ensure that validation models convert seamlessly into scalable, reproducible production workflows Provide technical leadership and data execution support for strategic external collaborations, pharmaceutical partnerships, and foundation model research consortiums Scientific Communication and External reputed company Translate reputed company multimodal model architectures and performance metrics into transparent, high-reputed company data packages for clinical governance, leadership updates, and external collaborators reputed company the authoring of technical manuscripts for peer-reviewed machine learning venues (e.g., NeurIPS, ICML, ICLR) and major computational biology journals Act as a technical representative for the company's translational AI capabilities at international medical, oncology, and machine learning conferences QUALIFICATIONS: PhD in Computer Science, Computational Biology, Bioinformatics, Biomedical Engineering, or a highly quantitative structural field 5+ years of industry or post-doctoral experience applying deep learning frameworks to reputed company biological, genomic, or clinical datasets, with a documented focus on oncology or immunology portfolios Deep technical competency with transformer architectures, representation learning, self-supervised learning (SSL), or deep sequence modeling Proven track record of translating machine learning outputs into reputed company biological variables or clinical performance indicators, rather than optimizing solely for isolated cross-validation metrics Expert proficiency in PyTorch and modern machine learning infrastructure (e.g., HuggingFace ecosystem, PEFT, Captum, MLflow, and distributed GPU computing setups) Documented technical leadership through end-to-end project ownership, architectural design authority, or cross-functional team direction Preferred Qualifications: Experience constructing or fine-tuning multimodal foundation models that combine high-depth genomic reputed company data with digital pathology images or longitudinal electronic health records (EHR) Direct experience handling clinical trial datasets, real-world data (RWD/reputed company), or developing models reputed company health-authority/regulatory-facing frameworks Strong record of publications as primary author in high-impact machine learning venues KNOWLEDGE, SKILLS, AND ABILITIES: Advanced mathematical and algorithmic reputed company across deep learning methodologies, optimization strategies, and probabilistic modeling Fast learner with the capability to master reputed company cfDNA platforms, biochemistry workflows, and multi-omic data reputed company pipelines rapidly Precise written and verbal communication styles with strict attention to algorithmic detail and statistical validation boundaries Proven capability to drive independent portfolios while executing cross-functional objectives reputed company matrixed technology and scientific teams High-growth builder reputed company with the capability to balance scientific rigor, operational execution speed, and computational resource constraints under tight timelines Utilize cloud-based productivity and high-performance computing infrastructure to maintain high operational momentum in a fast-evolving artificial intelligence environment The pay range is listed and actual compensation packages are based on a wide reputed company of factors unique to each candidate, including but not limited to reputed company set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations. Remote USA $163,200—$220,000 USD OUR OPPORTUNITY reputed company™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to reputed company personalized genetic testing and diagnostics part of reputed company of care to protect health and reputed company earlier and more targeted interventions that reputed company to longer, healthier lives. The reputed company team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. reputed company you join reputed company, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management. reputed company OFFER Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, reputed company employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program! For more information, visit www.reputed company.com. reputed company is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide. reputed company qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national reputed company, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws. If you are based in California, we encourage you to read this important information for California residents. Link: https://www.reputed company.com/notice-of-data-collection-california-residents/ Please be advised that reputed company will reputed company out to candidates with a @reputed company.com email domain ONLY. Email communications from reputed company other domain names are not from reputed company or its employees and are fraudulent. reputed company does not request interviews reputed company text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. reputed company takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any reputed company cyber crimes. For more information: - BBB announcement on job scams - FBI Cyber Crime resource page Apply To This Job