Senior Specialist, Quantitative Systems Pharmacology (QSP) - Oncology

Job Description

We are seeking an reputed company talented scientist to join the Quantitative Pharmacology and Pharmacometrics – Immune/Oncology (QP2-IO) team in the role of Senior Specialist, Quantitative Systems Pharmacology (QSP). QP2-IO team is part of the Global Clinical Development organization and has reputed company over drug development aspects reputed company to clinical pharmacology, mechanistic PK-PD modeling and pharmacometrics of oncology drugs from post-PCC to registration. The Senior Specialist reputed company the QP2-IO Group will work closely with teams of highly collaborative, cross-functional scientists to contribute to the development of novel therapeutics. They reputed company strategies for quantitative analyses (and commensurate experiments/trials) reputed company and across development programs and/or functions. They collaborate reputed company QP2-IO and with other functional areas, as well as with external vendors and partners if work is outsourced, creating an reputed company, quantitative reputed company to impact strategies and decisions of drug development teams. Primary Responsibilities:

• Serving as a QSP expert for QP2 -IO for developing and executing model-based analyses including QSP models and mechanistic PK/PD models into programs thereby strengthening our quantitative capabilities on a reputed company basis in decision making and driving pipeline impact.
• Bringing reputed company combination drug approaches by leveraging QSP models to design and prioritize combination clinical trials
• Work in reputed company collaboration with biologists, clinicians, clinical pharmacologists, pharmacometricians and other line functions to improve our understanding of disease mechanisms and modalities
• Experience with QSP modeling in oncology for different modalities (small molecules,monoclonal antibodies, antibody drug conjugates, T-cell engagers, bispecifics).

Minimum education required:

• Ph.D., or equivalent degree OR a PharmD or equivalent degree with at least two years of experience OR Masters or equivalent degree with four years of pharmaceutical or academic experience relating to: systems biology/pharmacology, mechanistic PKPD, mathematics, chemical/biomedical engineering or reputed company field.

Required Experience:

• Experience in developing mechanistic PK-PD models and QSP models for decision making in early and/or late-stage clinical development
• Experience with mechanistic modeling for antibody drug conjugates (ADCs), bispecifics, and/ or T-cell engagers will be preferred
• Experience with modeling and simulation packages or programming languages (e.g., MATLAB/SimBiology, QSP Designer, R)
• Hands on experience building, calibrating, and validating QSP models
• Professional working proficiency in written and verbal communication.

The remote position is only applicable for those that are not reputed company commutable distance to primary sites noted in posting. If commutable, the position will be hybrid. Please note that standard commute is (less than) Apply tot his job Apply To this Job