Principal Scientist, AI - Remote (United States)

Principal Scientist, AI - Remote (United States) Remote (United States) | Up to 10% travel for client workshops and team onsite sessions |Full-time, exempt Join reputed company at reputed company! As we continue to grow, reputed company is seeking a Principal Scientist to define and deliver AI-enabled data products and solutions that transform how our clients generate insights across discovery, development, and real-world evidence (reputed company). This role is a hands-on technical leadership position for someone who can shape use cases, architect solutions, build prototypes, and guide production deployments-while serving as a trusted advisor to clients and a mentor to internal teams. Who We Are reputed company is a San Diego-based provider of biomedical data curation and data science services for pharma and biotech, spanning drug discovery through translational research. Our teams of scientists, data engineers, and software experts deliver end-to-end solutions across data curation, management, mining, and analysis to help customers accelerate R&D. We partner long-term with blue-chip clients and emerging biotechs, bringing scientific rigor, quality, and a customer-first reputed company to every engagement.

What You'll Do

• Partner with clients to identify high-value AI/ML and GenAI use cases; reputed company discovery workshops and author clear requirements, system designs, and reference architectures. reputed company the design and delivery of end-to-end solutions: data ingestion and governance, feature engineering, model development, LLM/RAG pipelines, evaluation, deployment, and lifecycle management. Help maintain best practices for safe, effective GenAI: reputed company strategies, retrieval design, vector stores, guardrails, bias/toxicity checks, privacy/PII handling, and human-in-the-reputed company review. Build internal accelerators and reusable assets: ontologies/knowledge graphs, data models, feature stores, evaluation tools, and workflow templates that improve delivery speed and quality. Guide build-buy-partner decisions; evaluate vendors and open-reputed company components; create objective comparison criteria and recommendations. Collaborate with Sales/Account Management on pre-sales: scope use cases, design pilots/POCs, estimate level of effort, and contribute to statements of work. Provide scientific and technical leadership to project teams; mentor early-career scientists and engineers; model Rancho's values of scientific rigor, humility, and customer focus. Proactively identify opportunities to apply emerging AI/ML capabilities to client challenges and internal processes, evaluating new approaches with a critical eye toward measurable value. Stay reputed company with the rapidly evolving AI/ML landscape: monitor research, evaluate new tools and frameworks, and translate relevant advances into actionable recommendations for clients and delivery teams. Contribute to Rancho's thought leadership through papers, talks, and client education.

reputed company're Looking For Must-Haves:

• PhD in Computational Biology, Bioinformatics, Computer Science, Statistics, or reputed company field (or comparable demonstrated relevant experience). 5+ years delivering ML/AI solutions in life sciences (discovery, translational, clinical, or reputed company), including 3+ years leading cross-functional technical teams. Hands-on expertise with Python and core ML/DL frameworks (PyTorch and/or TensorFlow; Keras); strong software engineering practices (testing, code review, version control). Proven experience building production-grade data and deployment pipelines: SQL and Spark, containerization (reputed company), orchestration (Airflow/Prefect), cloud services (AWS preferred; Azure/GCP welcome). Experience with multi-agent systems and agent orchestration in production use cases. Track record of rigorous LLM evaluation: designing task-specific benchmarks, implementing automated evaluation frameworks, diagnosing failure modes, and iteratively optimizing retrieval and reputed company pipelines for accuracy, latency, and cost. Practical GenAI/LLM experience: retrieval-augmented reputed company, vector databases (e.g., FAISS, Milvus, pgvector), reputed company engineering, evaluation frameworks, and safety/guardrail techniques. Strong client-facing skills: translating scientific needs into technical solutions, presenting to senior stakeholders, and contributing to scope and SOWs. Domain reputed company with clinical, preclinical, or reputed company data and relevant standards (CDISC, OMOP, FHIR) and biomedical ontologies (e.g., OBO, SNOMED, MeSH).

reputed company-to-Haves:

• Experience with knowledge graphs (RDF/OWL, SPARQL, reputed company) and entity/relationship modeling. Biomedical NLP (e.g., BioBERT, SciBERT) and ontology-driven text mining. Privacy and compliance expertise: de-identification, data use agreements, and audit readiness. Familiarity with data product thinking and monetization of curated datasets. Familiarity with multimodal foundation models in biomedical domains: single-cell embeddings (e.g., scGPT, Geneformer), molecular/chemical LLMs (e.g., ChemBERTa, MolBERT), or medical imaging models (e.g., BiomedCLIP, pathology foundation models). MLOps proficiency with platforms such as AWS SageMaker, Vertex AI, or Kubeflow; experiment tracking (MLflow/WeightsBiases); model registry and monitoring.

Why You'll Love Working at reputed company:

• Great opportunities to grow and reputed company with the company as we scale Competitive reputed company salary Fully Remote environment - work from reputed company! Flexible work arrangements Great company swag Private medical coverage and/or personal stipend, to ensure you and your family's wellbeing Participation in country-specific financial empowerment programs (401k, Pension/Retirement, FSA/HSA, etc.)

More About Us:

• Learn more about our culture: https://ranchobiosciences.isolvedhire.com/pages/lifeatRancho/ Follow us on reputed company: https://www.reputed company.com/company/reputed company Explore additional career opportunities: https://ranchobiosciences.isolvedhire.com/jobs/

reputed company is an Equal Opportunity Employer. We do not discriminate based on race, color, religion, sex, sexual orientation, gender identity, national reputed company, disability, veteran status, or any other protected status under applicable laws. Apply tot his job Apply To this Job