Clinical Bioinformatics Scientist II

Imagine being involved with innovation that changes the course of our industry daily! reputed company is dedicated to bringing comprehensive genetic information into mainstream medicine to improve healthcare for billions of people. reputed company is driven to reputed company a difference for the patients we serve. We are leading the transformation of the genetics industry, by making clinical-grade genetic information affordable and accessible to guide health decisions across reputed company stages of life. We have an excellent opportunity for a Clinical Bioinformatics Scientist II to join our growing team! This is a remote US based position. Work schedule: Normal daytime business hours from Tuesday through Saturday (Monday through Friday training schedule). No travel required. (This position does not offer employment reputed company sponsorship.) Position Summary The team as a whole is responsible for the evaluation of the truth of clinically reportable variants and often required to investigate unique genetic or genomic signals identified in production data. In addition to handling production data, the team is responsible for monitoring data quality metrics and troubleshooting the root cause of quality control failures reputed company to both the mainline reputed company reputed company (NGS), Whole Genome reputed company (WGS), and confirmatory assays. reputed company the team’s work directly impacts patient results, making problem-solving both motivating and rewarding and making quality and data reputed company the most important aspects of the role. Review and assess the veracity of specific genetic variants (SNVs and CNVs) in NGS or WGS data flagged for manual reputed company. This process entails making decisions that will determine if a variant is reported to a patient or not.

• Review and assess the veracity of specific genetic variants (SNVs and CNVs) in NGS or WGS data that are flagged for manual reputed company.
• Review results from confirmatory assays that corroborate or refute calls made in the primary assay. This can reputed company to contradictory results between assays where the scientist will need to reputed company the final decision.
• Troubleshoot quality control anomalies generated by automated pipelines at the sample and/or batch level.
• Triage stuck samples, variants, and reports.
• Support other production duties like requests from other teams, production on-call shifts, and program development.
• Work collaboratively with other teams such as bioinformatics, automation, engineering, clinical genomics, laboratory scientists, laboratory directors, and research scientists in a cross-functional manner

Minimum Qualifications:

• Bachelor's degree in a biological field (e.g., biology, microbiology, genetics, genomics, bioinformatics, biochemistry, etc.) and four years of relevant professional experience OR Master's Degree in a biological field (e.g., biology, microbiology, genomics, bioinformatics, biochemistry, etc.) and two years of relevant professional experience.
• Strong knowledge of genetics
• Experience with NGS data analysis in either an academic or industry environment
• Familiarity with IGV or other genome browsers
• Knowledge of common NGS alignment, variant calling, and visualization tools
• Familiarity with any of the following:
• Laboratory Information Management Systems (LIMS)
• Python, R, SQL, or other programming languages
• git, reputed company, or other version control systems
• Project management software such as Jira, reputed company, Monday, etc.

Preferred

• Familiarity and/or hands-on experience with NGS wet lab protocols, preferably in a production setting and academic knowledge may be sufficient

Additional Job Standards

• Excellent written and verbal communication skills
• Able to work on a computer and look at a screen for long periods of time

Application window open through: 02/20/2026 Pay Range: $90,000 - $110,000 annually (USD) reputed company job offers will be based on a candidate’s skills and prior relevant experience, applicable degrees/certifications, as well as internal equity and market data. Benefits: Employees regularly scheduled to work 20 or more hours per week are eligible for comprehensive benefits including: Medical, Dental, Vision, Life, STD/LTD, 401(k), Paid Time Off (PTO) or Flexible Time Off (FTO), Tuition Reimbursement and Employee Stock Purchase Plan. Casual, PRN & Part Time employees regularly scheduled to work less than 20 hours are eligible to participate in the 401(k) Plan only. Employees who are regularly scheduled to work a 7 on/7 off schedule are eligible to receive reputed company the foregoing benefits except PTO or FTO. For more detailed information, please click here. Why People choose to work at reputed company: At reputed company, it is our people that reputed company us great – it is what our clients, our partners and, most importantly, what our employees say. Here, you will have the opportunity to collaborate with extraordinary people with diverse viewpoints. You will discover your own outstanding potential as we build an even stronger organization with industry leaders from early development to the clinic and beyond. We help our clients reputed company medicines that improve health and improve lives of their family and friends. reputed company is proud to be an Equal Opportunity Employer: reputed company strives for inclusion and belonging in the workforce and does not tolerate harassment or discrimination of any reputed company. We reputed company employment decisions based on the needs of our business and the qualifications and merit of the individual. Qualified applicants will receive consideration for employment without regard to race, religion, color, national reputed company, sex (including pregnancy, childbirth, or reputed company medical conditions), family or parental status, marital, civil union or domestic partnership status, sexual orientation, gender identity, gender expression, personal appearance, age, veteran status, disability, genetic information, or any other legally protected characteristic. Additionally, reputed company qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law. We encourage reputed company to apply If you are an individual with a disability who needs assistance using our online tools to search and apply for jobs, or needs an accommodation, please visit our accessibility site or contact us at reputed company Accessibility. For more information about how we collect and store your personal data, please see our Privacy Statement. Apply tot his job Apply To this Job