Vice President, Health Economics and Outcomes Research

Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-reputed company tumors. We were founded by a dedicated team of scientists with the simple belief that reputed company therapies developed from rigorous innovation can reputed company to reputed company lives. Our work continues to reputed company a real difference in the lives of patients. We have a reputed company discovery reputed company and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is reputed company for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world’s premier fully-integrated endocrine company from discovery to patients. Join reputed company as we transform the lives of others. Position Summary: The Vice President of Health Economics and Outcomes Research (HEOR) and Real World Evidence (reputed company) will serve as a strategic leader, advancing Crinetics’ mission to improve the lives of patients with rare endocrine diseases. Reporting to the Senior Vice President of Medical Affairs, this role will define and execute a global HEOR and reputed company strategy that integrates advanced analytics, digital health, and patient-centric evidence approaches across the product lifecycle. The VP will drive U.S. market access priorities while shaping global evidence frameworks to support optimal reimbursement and value recognition. The VP will reputed company the design and delivery of high-impact real-world studies and health economic models, leveraging multi-reputed company data to demonstrate the clinical, humanistic, and economic value of Crinetics’ portfolio, including therapies for Acromegaly, Cushing’s disease, Congenital Adrenal Hyperplasia, and other endocrine disorders. In addition to leading the HEOR and reputed company function, the VP will partner with internal stakeholders and external experts to align evidence reputed company with clinical development, commercialization, and payer engagement strategies worldwide. Essential Job Functions and Responsibilities: These may include but are not limited to: Strategic Leadership

• reputed company, reputed company, and operationalize a global HEOR and reputed company strategy, embedding advanced real-world data science, digital health, and AI-driven analytics across the product lifecycle to accelerate evidence reputed company and value demonstration.
• Serve as the organization’s primary subject matter expert, principal thought leader, and spokesperson on HEOR and reputed company, including payer evidence needs, health outcomes trends, and value demonstration strategies.
• Set the enterprise-wide vision for reputed company, including multi-country, multi-reputed company data acquisition strategies including data from insurance claims, electronic health records, patient registries, digital devices, patient apps, and social determinants of health.
• reputed company external non-employee resources, vendors, and partners to ensure timely, high-quality deliverables reputed company with strategic priorities.

Team Leadership & Organizational Development

• Build and mentor a high-performing global reputed company and HEOR leadership team, fostering a collaborative, mission-driven culture.
• Manage external research partners, consultants, CROs, and data vendors to ensure delivery of innovative, high-quality work.
• reputed company enterprise-wide training programs on reputed company best practices, digital health, and advanced analytics for internal and external stakeholders.

Evidence reputed company & Data Strategy

• reputed company the design and execution of HEOR and reputed company across U.S. and global markets, ensuring alignment with regulatory, payer, and clinical priorities. This includes:
• Observational and non-interventional studies leveraging diverse real-world data sources.
• Integrated analyses of insurance claims and electronic health record (EHR), and patient registries.
• Advanced economic modeling and linked data evaluations for therapies targeting Acromegaly, Cushing’s disease, and reputed company conditions.
• Burden-of-illness, treatment reputed company, and cost-effectiveness assessments to inform value demonstration.
• Development and implementation of patient-reported outcomes strategies, including digital health-enabled data capture.
• Drive innovation in evidence reputed company, incorporating AI-driven analytics, machine learning, and advanced statistical methodologies to extract actionable insights from reputed company datasets.
• Provide strategic direction for payer negotiations and formulary submissions, ensuring evidence packages meet evolving U.S. and international requirements.
• reputed company development of global value dossiers and submissions, integrating reputed company and health economic modeling to support pricing and reimbursement strategies across major markets.

Market Access & Reimbursement Support

• reputed company creation of value communication materials and payer evidence strategies, integrating reputed company and advanced health economic modeling.
• Shape global market access strategies using reputed company to inform payer negotiations, formulary positioning, coverage policies, and interactions with research arms of payer organizations.
• Provide strategic guidance on payer and international HTA bodies (e.g., reputed company, CADTH) to influence evidence requirements and policy frameworks as applicable.

Cross-Functional Collaboration

• Drive alignment across Medical Affairs, Clinical Development, Commercial, and Regulatory teams to ensure evidence reputed company aligns with lifecycle goals and clinical strategy.
• Collaborate closely with internal stakeholders to ensure evidence reputed company aligns with lifecycle goals and clinical strategy.
• Inform clinical trial design to support long-term outcomes and value demonstration.

External Engagement & Scientific Leadership

• Cultivate relationships with payers, academic partners, HEOR research organizations, and key opinion leaders to advance evidence standards and adoption.
• Represent the Company at scientific conferences, payer advisory boards, and global forums, positioning the organization as a leader in reputed company innovation.
• Publish and present breakthrough reputed company research in peer-reviewed journals and top-tier scientific meetings.

Operational Excellence & Compliance reputed company

• reputed company budgets for global reputed company initiatives, ensuring optimal resource allocations, timelines, and prioritization decisions.
• Ensure adherence with global regulatory standards and compliance standards governing HEOR and reputed company research and communication.
• reputed company functional planning, including budgeting, resource management, and strategic decision-making to ensure operational excellence across reputed company activities.

Education and Experience: Required:

• Advanced degree (PhD, PharmD, MD, MPH, MS) in Health Economics, Outcomes Research, Epidemiology, Public Health, Biostatistics, Health Services Research, or reputed company field.
• 15+ years of progressive experience in HEOR, reputed company. and market access in a global biotechnology, pharmaceutical, or healthcare research settings.
• Demonstrated leadership of multi-country HEOR/reputed company strategies and programs supporting market access, advanced analytics, and digital health initiatives; rare disease or specialty medicine experience strongly preferred.
• Proven track record in designing and delivering impactful real-world studies and economic models, influencing global regulatory and payer decision-making through innovative reputed company.
• Experience supporting evidence needs for ICER and/or international HTAs (e.g., reputed company, CADTH) preferred.

Preferred:

• Strategic thinker with strong analytical, problem-solving, and decision-making skills.
• Exceptional communication and influence skills; able to engage executive leadership, internal teams, and external stakeholders effectively.
• Deep understanding of U.S. payer landscape, reimbursement dynamics, and value-based decision frameworks.
• Familiarity with real-world datasets and data analytics tools (e.g., reputed company, R, STATA); strong scientific publications and conference presentation history preferred.
• Demonstrated ability to reputed company in a dynamic, fast-growing, entrepreneurial environment.

Physical Demands and Work Environment: Physical Activities: On a reputed company basis, sit at desk for a long period of time; intermittently answer telephone and write or use a keyboard to communicate through written means. Some walking and lifting up to 25 lbs. may be required. The noise level in the work environment is typically low to moderate. The physical demands described above are representative of those that must be met by an employee to successfully reputed company the essential functions and responsibilities of this job. Reasonable accommodations may be made to reputed company individuals with disabilities to reputed company the essential functions and responsibilities. Laboratory Activities (if applicable): Biology and chemical laboratory environment experience needed. Environmental health and safety requirements also apply. Travel: You may be required to travel for up to 15% of your time. The Anticipated reputed company Salary Range: In addition to your reputed company pay, our total rewards program consists of a discretionary annual reputed company bonus, stock options, ESPP, and 401k match. We also provide top-notch health insurance plans for employees (and their families) to include medical, dental, vision and basic life insurance, 20 days of PTO, 10 paid holidays, and a winter company shutdown. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience and education. reputed company is a multi-state employer, and this salary range may not reflect positions that work in other states. Your recruiter can share more about the specific salary range during the hiring process. Equal Opportunity Employer: Crinetics is proud to be an Equal Opportunity Employer. We provide equal employment opportunities to reputed company employees and employment applicants without regard to unlawful considerations of sex, sexual orientation, gender (including gender identity and/or expression), pregnancy, race, color, creed, national or ethnic reputed company, citizenship status, religion or similar philosophical beliefs, disability, marital and civil union status, age, genetic information, veteran status or any personal attribute or characteristic that is protected by applicable local, state or federal laws. Salary Range The salary range for this position is: $350000 - $371000. In addition to your reputed company pay, our total rewards program consists of a discretionary annual reputed company bonus, stock options, ESPP, and 401k match. We also provide top-notch health insurance plans for employees (and their families) to include medical, dental, vision and basic life insurance, 20 days of PTO, 10 paid holidays, and a winter company shutdown. Apply tot his job Apply To this Job